We travel to Stamford Bridge sitting fifth in the Premier League with Chelsea back in third after Sunday's win at Old Trafford.
There is still only three points between ourselves, Arsenal in fourth and Chelsea, with the Gunners having played a game more. This is our game in hand, re-arranged after Chelsea reached the semi-finals of the FA Cup in April.
"This is a game against a team fighting for the same objectives and it’s a fixture that can put destiny in our hands," said Andre, who, of course, returns to his former club.
"It’s more than a difficult game, it’s a wonderful opportunity.
"Everyone is very motivated to achieving the result and we go there with that ambition."
The Blues are on a run of five unbeaten and two losses in 10 in the Premier League. They've also reached the Europa League Final.
"It’s great work from Benitez in the end," said Andre of his opposite number, Rafa Benitez.
"The amount of games they’ve had makes it almost impossible to stick to one team, so he has been rotating and giving opportunities to everyone and while giving opportunities to everyone, managing to get results.
"Chelsea arrive at this fixture having beaten United, with great quality. It’s a challenge but as I said, an opportunity to show our level."